Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion
نویسندگان
چکیده
منابع مشابه
Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion.
Muscarinic receptors (CHRM) are overexpressed in colon cancer. To explore a role for muscarinic receptor signaling in colon cancer metastasis, we used human H508 and HT29 colon cancer cells that coexpress epidermal growth factor (ERBB) and CHRM3 receptors. In a wound closure model, following 8-h incubation of H508 cells with 100 μM ACh we observed a threefold increase in cell migration indistin...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology
سال: 2011
ISSN: 0193-1857,1522-1547
DOI: 10.1152/ajpgi.00306.2010